Transcriptional and Cellular Diversity of the Human Heart

Nathan R. Tucker, Mark Chaffin, Stephen J. Fleming, Amelia W. Hall, Victoria A. Parsons, Kenneth C. Bedi Jr, Amer-Denis Akkad, Caroline N. Herndon-, Alessandro Arduini, Irinna Papangeli, Carolina Roselli, François Aguet, Seung Hoan Choi, Kristin G. Ardlie, Mehrtash Babadi, Kenneth B. Margulies, Christian M. Stegmann, Patrick T. Ellinor

Last updated on Jun 16, 2021

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Pinto Lab - Baker Heart and Diabetes Institute

Abstract

The human heart requires a complex ensemble of specialized cell types to perform its essential function. A greater knowledge of the intricate cellular milieu of the heart is critical to increase our understanding of cardiac homeostasis and pathology. This publication has applied single-cell RNA sequencing to assess the cellular and transcriptional diversity of the nonfailing human heart.

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The raw data can be downloaded through dbGab accession number phs001539.v1.p1.

human heart