The CardiovascuLAR Atlas - CLARA - was developed to easily and interactively explore cellular landscapes of cardiovascular tissues and others that influence cardiovascular health.
Single-cell omics is the profiling of a variable — such as protein, RNA or DNA — in individual cells in order to understand a complex biological system. Application of these technologies have transformed our understanding of cardiovascular tissues such as the heart and aorta, and other organs and tissue systems that influence cardiovascular development, homeostasis or dysfunction. Single-cell approaches have revealed the complex heterogeneity of cell types that form cardiovascular tissues and their dense intercellular communication networks. Here we present CLARA — CardiovascuLAR Atlas — for exploring cardiovascular cellular landscapes using single-cell transcriptomic data. Version 1.X of CLARA includes data from human and mouse hearts and aortas, and from healthy and diseased contexts. In addition to the data exploration portal, we have also incorporated additional resources such as Cell type definitions and Methods to better understand cell types within datasets, and how datasets were prepared.
FOR FULL DESCRIPTION OF CLARA AND ITS UTILISATION PLEASE SEE DONA ET AL., 2021
Learn more about the datasets used in this portal
Find out the approaches used to analyse the data
Explore the cells found in the datasets