Macrophages

Confocal micrograph of double positive staining of Mrc1 (red) and Cx3cr1 (green) cells highlighting the presence of macrophages in the murine heart. Pinto Lab - Baker Heart and Diabetes Institute

Tissue-resident immune cells involved in tissue maintenance. The many functions of macrophages include detection of tissue damage or pathogens, efferocytosis (clearance of dying or dead cells), phagocytosis of tissue debris and foreign particles, and regulation of inflammation.

Marker genes: Csf1r, Adgre1, Mrc1.

Abbreviated cell population name(s): Mac (e.g. “Mac”, or “Mac1”, “Mac2”…).